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FDA approves injectable PrEP
2021-12-24
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This article shared 1009 times since Fri Dec 24, 2021
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The U.S. Food and Drug Administration (FDA) approved Apretude (cabotegravir extended-release injectable suspension) for use in at-risk adults and adolescents weighing at least 77 pounds for pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV, according to a press release.
Apretude is given first as two initiation injections administered one month apart, and then every two months thereafter. Patients can either start their treatment with Apretude or take oral cabotegravir (Vocabria) for four weeks to assess how well they tolerate the drug.
"[The] approval adds an important tool in the effort to end the HIV epidemic by providing the first option to prevent HIV that does not involve taking a daily pill," said Debra Birnkrant, M.D., director of the Division of Antivirals in the FDA's Center for Drug Evaluation and Research. "This injection, given every two months, will be critical to addressing the HIV epidemic in the U.S., including helping high-risk individuals and certain groups where adherence to daily medication has been a major challenge or not a realistic option."
According to the U.S. Centers for Disease Control and Prevention, notable gains have been made in increasing PrEP use for HIV prevention in the U.S. and preliminary data show that in 2020, about 25% of the 1.2 million people for whom PrEP is recommended were prescribed it, compared to only about 3% in 2015. |
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This article shared 1009 times since Fri Dec 24, 2021
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